A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Dmel\297

General Information
Symbol Dmel\297 Species D.melanogaster
Name 297 element FlyBase ID FBte0000675
Feature type natural transposable element Created / Updated 2006-12-04/2006-12-04
hide Sequences & Components
Complete element (bp)
6995
(Kaminker et al., 2002)
6995
 
Terminal repeat (bp)
415
 
Reference sequence transposon_sequence_set.embl.txt.gz
Component genes
297\pol
 
297\gag
 
297\env
 
hide Sequence Accessions
DDBJ/EMBL/GenBank
 
hide Sequence Ontology (SO)
Transposon type
LTR_retrotransposon
(Kaminker et al., 2002, )
transposable_element
(Kaminker et al., 2002, )
hide Insertions & Copy Number
Copy number
and comments
57 in euchromatin of Release 3 genome annotation, of which 18 are full length.
(Kaminker et al., 2002)
Approximately 30 (FBrf0032823)
 
Search for
Target Site Duplication
Size (bp)
4
 
hide Orthologs
Curated drosophilid orthologs
(Biemont and Cizeron, 1999)
 
hide Comments
Used in an investigation to address the relationship between retrotransposons and retroviruses and the coadaptation of these retroelements to their host genomes. Results indicate retrotransposons are heterogeneous in contrast to retroviruses, suggesting different modes of evolution by slippage-like mechanisms.
(Terzian et al., 1997)
Study of TE distribution (P-element, hobo, I-element, copia, mdg1, mdg3, 412, 297 and roo) along chromosome arms shows no global tendency for the TE site occupancy frequency to negatively follow the recombination rate, except for the 3L arm. The tendency for TE insertion number to increase from base to tip of some chromosome arms is simply explicable by a positive relationship with DNA content along the chromosomes. So for all TEs, except hobo, there is no relationship between distribution of TE insertion numbers weighted by DNA content and recombination rate. hobo insertion site number is positively correlated with recombination rate.
(Hoogland and Biemont, 1996)
The chromosomal distribution of a number of retrotransposons in an isolated population of D.melanogaster (from Ishigaki Island, Okinawa, Japan) has been determined.
(Suh et al., 1995)
The spatial and temporal expression patterns of fifteen families of retrotransposons are analysed during embryogenesis and are found to be conserved. Results suggest that all families carry cis-acting elements that control their spatial and temporal expression patterns.
(Ding and Lipshitz, 1994)
Estimating the genomic numbers of transposable elements demonstrates many families of element are over-represented in heterochromatin.
(Charlesworth et al., 1994)
The distribution of a number of transposable elements has been studied in 10 Harwich mutation accumulation lines.
(Nuzhdin and Mackay, 1995)
Element copy numbers on inversion and standard chromosomes has been determined. The copy number is significantly higher within low frequency inversions than within the corresponding standard chromosome regions.
(Sniegowski and Charlesworth, 1994)
Rates of transposition and excision of the 297 element have been determined.
(Nuzhdin and Mackay, 1994)
One substock of inbred lines shows considerable heterogeneity of insertion sites of copia (frequency of insertions is 12% per haploid genome per generation) whereas mdg1, 412, mdg3, gypsy, 297 and HMS-Beagle were stable in all stocks examined.
(Pasyukova and Nuzhdin, 1992)
Stability of 11 transposable element families compared by Southern blotting among individuals of lines that had been subjected to 30 generations of sister sib matings. 412, roo, blood, 297, 1731 and G-element all appear stable, whereas copia, hobo, I-element, gypsy and jockey elements show instability.
(di Franco et al., 1992)
Distribution of 9 families of transposable elements in a natural population was studied and the hypothesis that transposable element abundance is regulated primarily by deleterious fitness consequences of ectopic meiotic exchange was supported. Proximal euchromatin may only infrequently undergo exchange, and elements detected in population surveys of this kind tend to be inserted into sites where there is negligible effect on fitness.
(Charlesworth et al., 1992)
297 elements were first described by Potter et al. (FBrf0032823) but were originally identified by Wensink and Rubin as being complementary to abundant polyA RNA in tissue-culture cells.
 
Expression is enriched in embryonic gonads.
(Shigenobu et al., 2006)
hide Other Information
hide Etymology
hide External Crossreferences
Sequence Crossreferences
DDBJ/EMBL/GenBank
 
Other Crossreferences
hide Synonyms & Secondary IDs ( 8 )
Reported As
Symbol Synonym
297
(Saito et al., 2006, Shigenobu et al., 2006, Mito et al., 2005, Smith, 2007, Brennecke et al., 2007)
BarA
(Norris et al., 1992, FlyBase, 1996-)
BcDNA:SD08734
 
Dm297
(Leibovich, 1990, FlyBase, 1996-)
Dme297V
(Pelisson et al., 2002)
EG:EG0007.2
 
T1/T2
(Higashijima et al., 1992, Higashijima et al., 1992, FlyBase, 1996-)
Name Synonym
297 element
 
Secondary FlyBase IDs
  • FBgn0061365
  • FBgn0000005
  • FBtp0011407
hide References ( 102 )
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hide Recent research papers ( 4 )
Brennecke et al., 2007, Cell 128(6): 1089--1103
Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. [FBrf0200494]
Smith, 2007, Science 316(5831): 1586--1591
[FBrf0202564]
Saito et al., 2006, Genes Dev. 20(16): 2214--2222
Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. [FBrf0191820]
Shigenobu et al., 2006, Proc. Natl. Acad. Sci. USA 103(37): 13728--13733
Molecular characterization of embryonic gonads by gene expression profiling in Drosophila melanogaster. [FBrf0193273]
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