Dmel\17.6

General Information
Symbol	Dmel\17.6	Species	D.melanogaster
Name	17.6 element	FlyBase ID	FBte0000109
Feature type	natural transposable element	Created / Updated	2006-12-04/2006-12-04
Sequences & Components
Complete element (bp)	7439 (Kaminker et al., 2002) 7439
Terminal repeat (bp)	512
Reference sequence	transposon_sequence_set.embl.txt.gz
Component genes	17.6\pol 17.6\gag 17.6\env
Sequence Accessions
	DDBJ/EMBL/GenBank Z71029 Z70850 Z32339 Z32251 Z31854 X79394 X01472 V01518 V01517 M31574 M31573 M31571 M31570 M31569 M31567 M31566 M31565 M31564 M31563 M31562 M31561 L39084 BK001842 AL008791
Sequence Ontology (SO)
Transposon type	LTR_retrotransposon (Kaminker et al., 2002, ) transposable_element (Kaminker et al., 2002, )
Insertions & Copy Number
Copy number and comments	12 in euchromatin of Release 3 genome annotation, of which 7 are full length. (Kaminker et al., 2002) 40 (FBrf0040123)
Search for	All insertions of this transposon Insertions in the sequenced genome Insertions in other genomes
Target Site Duplication
Size (bp)	4
Orthologs
Curated drosophilid orthologs	Dsim\17.6 (Biemont and Cizeron, 1999)
Comments
	Used in an investigation to address the relationship between retrotransposons and retroviruses and the coadaptation of these retroelements to their host genomes. Results indicate retrotransposons are heterogeneous in contrast to retroviruses, suggesting different modes of evolution by slippage-like mechanisms. (Terzian et al., 1997) The chromosomal distribution of a number of retrotransposons in an isolated population of D.melanogaster (from Ishigaki Island, Okinawa, Japan) has been determined. (Suh et al., 1995) The spatial and temporal expression patterns of fifteen families of retrotransposons are analysed during embryogenesis and are found to be conserved. Results suggest that all families carry cis-acting elements that control their spatial and temporal expression patterns. (Ding and Lipshitz, 1994) Estimating the genomic numbers of transposable elements demonstrates many families of element are over-represented in heterochromatin. (Charlesworth et al., 1994) Element copy numbers on inversion and standard chromosomes has been determined. The copy number is significantly higher within low frequency inversions than within the corresponding standard chromosome regions. (Sniegowski and Charlesworth, 1994) Presence or absence of a long terminal repeat of 17.6 does not correlate with resistance or susceptibility to DDT in 31 strains of D.melanogaster and D.simulans from around the world. (Delpuech et al., 1993) Transposition rates of mobile elements in lines AW and JH, in which spontaneous mutations have accumulated for about 400 generations, are studied. 412 and 17.6 elements rate of transposition is very low, I-element and hobo insertions occur much more frequently. (Harada et al., 1990) A retroviral-like transposable element. First described by Saigo et al. (FBrf0036029) as a sequence inserted into histone genes and hybridizing to 297 elements. Expression is enriched in embryonic gonads. (Shigenobu et al., 2006)
Other Information
Etymology

External Crossreferences
Sequence Crossreferences
	DDBJ/EMBL/GenBank Z71029 Z70850 Z32339 Z32251 Z31854 X79394 X01472 V01518 V01517 M31574 M31573 M31571 M31570 M31569 M31567 M31566 M31565 M31564 M31563 M31562 M31561 L39084 BK001842 AL008791
Other Crossreferences

Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	17.6 (ffrench-Constant et al., 2006, Shigenobu et al., 2006, Minervini et al., 2007, Gunawardane et al., 2007, Smith, 2007, Brennecke et al., 2007) 17.6S (Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24, Inouye, 1995.1.24) Dme176V (Pelisson et al., 2002) HDC07673
Name Synonym	17.6 element
Secondary FlyBase IDs
	FBgn0000004 FBtp0011399
References ( 85 )

Generate a list of	All references relating to this natural transposable element ( 85 )

List References by type	Research paper ( 57 ) Supplementary material ( 1 ) Review ( 9 ) Abstract ( 3 ) FlyBase analysis ( 1 ) DNA/RNA sequence record ( 12 ) Letter ( 1 ) Computer file ( 1 )
Recent research papers ( 4 )
	Brennecke et al., 2007, Cell 128(6): 1089--1103 Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. [FBrf0200494] Minervini et al., 2007, Gene 393(1-2): 1--10 Heterochromatin protein 1 interacts with 5'UTR of transposable element ZAM in a sequence-specific fashion. [FBrf0200033] Smith, 2007, Science 316(5831): 1586--1591 [FBrf0202564] Shigenobu et al., 2006, Proc. Natl. Acad. Sci. USA 103(37): 13728--13733 Molecular characterization of embryonic gonads by gene expression profiling in Drosophila melanogaster. [FBrf0193273] Show all research papers ...
Recent reviews ( 1 )
	ffrench-Constant et al., 2006, BioEssays 28(1): 6--8 Resistance and the jumping gene. [FBrf0189798] Show all reviews ...