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Reference
Citation	Haoudi, A., Kim, M.H., Champion, S., Best-Belpomme, M., Maisonhaute, C. (1995). The Gag polypeptides of the Drosophila 1731 retrotransposon are associated to virus-like particles and to nuclei. FEBS Lett. 377(1): 67--72.
FlyBase ID	FBrf0085174
Type of publication	Research paper
Offprint Available	Yes
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PubMed ID	8543022
PubMed Abstract	1731 is a Drosophila melanogaster retrotransposon whose nucleotide sequence shows a proviral architecture with two long terminal repeats (LTRs) framing two internal Open Reading Frames (ORFs). The pol ORF2 of this mobile genetic element was demonstrated to code for an active Reverse Transcriptase (RT) and the ORF1 is expected to code for the structural Gag proteins of the virus-like particles (VLP). Using specific anti-Gag antibodies, we have characterized the 1731 Gag polypeptides expressed either in vitro or in Kc Drosophila melanogaster cultured cells. Together with the 1731 RT, the largest, likely post-translationaly-modified Gag polypeptides are gathered into cytoplasmic virus-like particles. Moreover and consistent with the nuclear localization signal present in the Gag sequence, we observed that a short 1731 Gag polypeptide is associated to the cell nuclei.
Biosis	98632186
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Language of publication	English
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Abbreviation	FEBS Lett.
Title	FEBS Letters (Federation of European Biochemical Societies)
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Volume range	1-
Year range	1968-
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Place of publication	Amsterdam
Language of publication	English
ISBN/ISSN	0014-5793
CODEN	FEBLAL
Data from Reference
Genes (2)
	1731\RTase 1731\gag
Natural transposons (1)
	1731