A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Reference Report

Reference
Citation Rabinow, L., Birchler, J.A. (1989). A dosage-sensitive modifier of retrotransposon-induced alleles of the Drosophila white locus.  EMBO J. 8: 879--889.
FlyBase ID FBrf0049635
Type of publication Research paper
Offprint Available Yes
External Crossreferences
PubMed ID 2542025
PubMed Abstract The apricot allele of the white locus results from the insertion of the retrotransposon copia. Mutations in a newly discovered locus, the Darkener-of-apricot (Doa), suppress wa and some of its revertants. Of 44 other white alleles tested, only wsp55 is affected by Doa, although, in contrast, it is enhanced by Doa mutations. The Doa locus modulates wa and wsp55 expression as a function of its own dosage. Mutations in Doa are dominant suppressors or enhancers and are recessive lethals. Rare Doa mutant homozygotes escaping lethality demonstrate extreme phenotypic suppression of wa and enhancement of wsp55. RNA from wa is substantially wild-type in structure in escapers, although reduced in quantity.
Biosis 87114984
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Language of publication English
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Abbreviation EMBO J.
Title The EMBO Journal
Authors
Volume range 1-
Year range 1982-
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Place of publication Oxford
Language of publication English
ISBN/ISSN 0261-4189
CODEN EMJODG
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hideAberrations (13)
hideAlleles (53)
hideConstructs (2)
hideGenes (10)
hideInsertions (16)
hideNatural transposons (4)