mutants exhibit partial embryonic lethality, a delay in emergence from eclosion, and reduced lifespan.
Embryonic hematopoiesis is not affected in Toll-9KO
mutants, indeed the number of larval hemocytes is slightly increased in Toll-9KO
mutant flies resist clean injury and septic injuries performed with either Gram-positive or Gram-negative bacteria just as well as control flies. The numbers of intestinal stem cells and young enterocytes are similar in unaffected Toll-9KO
mutants and control guts. Upon infection, the epithelium renewal occurs normally in Toll-9KO