General Information
Symbol
Dmel\GliDD.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0248972
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UAS regulatory sequences drive expression of Gli modified to carry two tyrosine substitutions (Y766D and Y790D), to mimic a constitutively-phosphorylated state.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Model Data
Disease Ontology
Models ( 0 )
Disease
Evidence
References
Interactions ( 0 )
Disease
Interaction
References
Comments ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Expression of GliDD.Scer\UAS in the wing imaginal disc under the control of Scer\GAL4ap-md544 does not result in any cell delamination or migration phenotypes. A significant increase in the number of dividing cells is observed in the dorsal compartment of the wing disc, and ectopic folds in the wing disc are seen. No cell death is observed in these wing discs.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Expression of GliDD.Scer\UAS under the control of Scer\GAL4da.G32 fully rescues the embryonic lethality of GliAE2Δ45 mutants. Rescued embryos develop into larvae, but the majority of these become paralysed and die. Adult escapers exhibit malformed legs and fail to inflate their wings.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
GliDD.Scer\UAS
GliDD.UAS
Name Synonyms
Secondary FlyBase IDs
    References (1)