General Information
Symbol
Dmel\Khc1-849.αTub67C.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0246619
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
The αTub67C promoter drives expression of a mutant "tailless" form of Khc that is missing the last 125 amino acid residues and which is tagged with GFP.
Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Model Data
Disease Ontology
Models ( 0 )
Disease
Evidence
References
Interactions ( 0 )
Disease
Interaction
References
Comments ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Approximately 60% of Khc1-849.αTub67C.T:Avic\GFP mutants oocytes exhibit incorrect nucleus positioning, with the nucleus found separated from the anterior membrane by more than half a nucleus radius. The presence of Khc1-849.αTub67C.T:Avic\GFP rescues the absence of dorsal appendages found in Khc27 mutants in 48% of cases. Only 3.5% of these mutants have two fully formed dorsal appendages. The presence of Khc1-849.αTub67C.T:Avic\GFP fails to rescue osk mRNA transport but does rescue the dynein transport defects found in Khc27 mutants.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments
The presence of Khc1-849.αTub67C.T:Avic\GFP fails to rescue osk mRNA transport but does rescue the dynein transport defects found in Khc27 mutants. Approximately 60% of Khc1-849.αTub67C.T:Avic\GFP mutants oocytes exhibit incorrect nucleus positioning, with the nucleus found separated from the anterior membrane by more than half a nucleus radius. The presence of Khc1-849.αTub67C.T:Avic\GFP rescues the absence of dorsal appendages found in Khc27 mutants in 48% of cases. Only 3.5% of these mutants have two fully formed dorsal appendages.
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Khc1-849.αTub67C.GFP
Khc1-849.αTub67C.T:Avic\GFP
Name Synonyms
Secondary FlyBase IDs
    References (2)