General Information
Symbol
Dmel\mgldsRNA.UAS.cKa
Species
D. melanogaster
Name
FlyBase ID
FBal0243332
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
The FRT cassette has been excised, allowing expression of the inverted repeat of mgl-RB nucleotides 11821-12342 from the UAS regulatory sequences.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Model Data
Disease Ontology
Models ( 0 )
Disease
Evidence
References
Interactions ( 0 )
Disease
Interaction
References
Comments ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
The cuticle of the adult wing blade is dull and opaque in flies expressing mgldsRNA.Scer\UAS.cKa under the control of Scer\GAL4C-765. When mgldsRNA.Scer\UAS.cKa is expressed under the control of Scer\GAL4en-e16E, flies emerge with intact wings. However, after several days, the posterior wing blade appears frayed and broken, while the anterior part of the wing remains intact, suggesting that the cuticle secreted by cells expressing Scer\GAL4en-e16E is more fragile than normal. Expression of mgldsRNA.Scer\UAS.cKa under the control of Scer\GAL4ap-md544 does not perturb the formation of the outer envelope or epicuticle of the dorsal wing cuticle during pupal development. The thickness of the developing procuticle appears normal, but fissures in the distal procuticle are seen, which become more numerous with time, such that the procuticle of adult wings is dramatically cracked and split.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
MegalindsRNA.Scer\UAS
mgldsRNA.Scer\UAS.cKa
mgldsRNA.UAS.cKa
Name Synonyms
Secondary FlyBase IDs
    References (2)