The expression of DifdsRNA.IR.Scer\UAS
under the control of Scer\GAL4c564
blocks the normal inflammatory response to Gram-positive bacterial infection (assessed by the expression levels of Drosomycin), but has no significant effect in basal (non-infected) conditions, as compared to controls.
Flies expressing DifdsRNA.IR.Scer\UAS
, under the control of Scer\GAL4da.G32
exhibit impaired immune response . They exhibit a dramatic loss of survival rate after infection with E.faecalis (gram-positive bacterium). This is mirrored to a lesser extent, when these flies are infected with B.bassiana (filamentous fungus) or C.albicans (yeast).