General Information
Symbol
Dmel\wtsP8
Species
D. melanogaster
Name
FlyBase ID
FBal0044516
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference
Deletion of DNA flanking the wtsP509-19 P{lacW} insertion, probably in the proximal direction, without loss of the distal P{lacW} sequences.
Insertion components
P{lacW}wtsP8
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Model Data
Disease Ontology
Models ( 0 )
Disease
Evidence
References
Interactions ( 0 )
Disease
Interaction
References
Comments ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Homozygotes die as pupae. Eyes are typically rough and show overproliferation.
Homozygotes exhibit embryonic or early larval lethality. wts tumour phenotype in mitotic clones: overproliferation and apical hypertrophy of epithelial cells leading to abnormal deposition of cuticle.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
wtsP8 has hyperplasia phenotype, suppressible by Cdk1B47
wtsP8 has hyperplasia phenotype, suppressible by CycA5
wtsP8 has size defective | adult stage phenotype, suppressible by Cdk1B47
Other
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference
wtsP8 has eye phenotype, suppressible by Cdk1B47
wtsP8 has eye phenotype, suppressible by CycA5
Additional Comments
Genetic Interactions
Statement
Reference
The lethality and overproliferation phenotype are rescued if the fly carries one copy of cdc2B47 or CycA5.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
wtsP8
Name Synonyms
Secondary FlyBase IDs
    References (2)