General Information
Symbol
Dmel\mirr6D1
Species
D. melanogaster
Name
FlyBase ID
FBal0031851
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
mirr-lacZ, mirror-lacZ, l(3)6D169D
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Insertion components
P{lacW}mirr6D1
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Model Data
Disease Ontology
Models ( 0 )
Disease
Evidence
References
Interactions ( 0 )
Disease
Interaction
References
Comments ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
Defects in encapsulation of the 16-cell cyst and separation from the germarium are seen in egg chambers of mirr6D1/mirre48 females. A reduction or loss of dorsal structures is seen in egg chambers; in stage 14 egg chambers the operculum has only 30 +/- 2.6 cell imprints (compared to the wild type number of 43 +/- 5.2). Dorsal appendages may be missing. Homozygous clones result in ventralisation of the egg chamber.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
mirr6D1 is a suppressor of egg phenotype of cicfet-U6/cicfet-T6
mirr6D1 is a suppressor of egg phenotype of cicfet-U6/cicfet-E11
mirr6D1 is a suppressor of egg phenotype of cicfet-U6/cicBA53
Additional Comments
Genetic Interactions
Statement
Reference
Approximately 0.5% of cicfet-T6/mirr6D1 cicfet-U6 females exhibit a weak eggshell phenotype. The dorsal midline is expanded and the appendages are broader and positioned laterally with a trace of ventral collar material. Approximately 42.6% of cicfet-U6/mirr6D1 cicfet-T6 females exhibit a moderate eggshell phenotype. The dorsal midline is expanded and the appendages are broader and positioned laterally and exhibit a ventral collar of ectopic appendage-like material. The dorsalmost region remains free of appendage material. Approximately 42.1% of cicfet-U6/mirr6D1 cicfet-T6 females exhibit a moderate-severe eggshell phenotype. The dorsal midline is expanded and the appendages are broader and positioned laterally and exhibit a thick ventral collar of ectopic appendage-like material. The dorsalmost region remains free of appendage material. None of the cicfet-U6/mirr6D1 cicfet-T6 females exhibit a severe eggshell phenotype (compared to 1.7% in the heterozygote). There is an increase in the weak phenotype, and a decrease in the severe phenotype compared to the cicfet-T6/cicfet-U6 mutant, indicating that mirr6D1 suppresses the cicfet-T6/cicfet-U6 phenotype. Approximately 34.4% of cicfet-E11/mirr6D1 cicfet-U6 females exhibit a weak eggshell phenotype. Approximately 37.4% of cicfet-U6/mirr6D1 cicfet-E11 females exhibit a weak-moderate eggshell phenotype. Approximately 24.5% of cicfet-U6/mirr6D1 cicfet-E11 females exhibit a moderate eggshell phenotype. There is an increase in the weak phenotype, and a decrease in the severe phenotype compared to the cicfet-E11/cicfet-U6 mutant, indicating that mirr6D1 suppresses the cicfet-E11/cicfet-U6 phenotype. Approximately 34.4% of cicfet-E11/mirr6D1 cicfet-U6 females exhibit a weak eggshell phenotype. Approximately 37.4% of cicfet-U6/mirr6D1 cicfet-E11 females exhibit a weak-moderate eggshell phenotype. Approximately 24.5% of cicfet-U6/mirr6D1 cicfet-E11 females exhibit a moderate eggshell phenotype. Approximately 37.9% of cicfet-U6/mirr6D1 cicfet-E11 females exhibit a moderate-severe eggshell phenotype. The dorsal midline is expanded and the appendages are broader and positioned laterally and exhibit a thick ventral collar of ectopic appendage-like material. The dorsalmost region remains free of appendage material. There is an increase in the weak phenotype, and a decrease in the severe phenotype compared to the cicfet-E11/cicfet-U6 mutant, indicating that mirr6D1 suppresses the cicfet-E11/cicfet-U6 phenotype. Approximately 0.5% of cicfet-U6/mirr6D1 cicBA53 females exhibit a moderate eggshell phenotype. The dorsal midline is expanded and the appendages are broader and positioned laterally and exhibit a ventral collar of ectopic appendage-like material. The dorsalmost region remains free of appendage material. Approximately 32.6% of cicfet-U6/mirr6D1 cicBA53 females exhibit a severe eggshell phenotype (compared to 85.9 in the heterozygote). The dorsal midline is expanded and the appendages are broader and positioned laterally and exhibit a pronounced ventral collar of ectopic appendage-like material, along with small anterior projections.There is an increase in the weak phenotype, and a decrease in the severe phenotype compared to the cicBA53/cicfet-U6 mutant, indicating that mirr6D1 suppresses the cicBA53/cicfet-U6 phenotype.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (6)